GeneBLAzer™ ADRA2A-Gqo5-NFAT-bla CHO-K1 cells contain the human Adrenoceptor A2A (ADRA2A) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line. GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cells (Cat. no. K1536) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Chimeric G protein, Gqo5.
The GeneBLAzer™ ADRA2A-Gqo5-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of UK 14,304. In addition, GeneBLAzer™ ADRA2A-Gqo5-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
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For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NM_000681.2
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
ADRA2A
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
ADRA2A
Cell Line
CHO-K1
System Type
GeneBLAzer™
Druggable Target
GPCRs
Contents & Storage
Contents: K1743 GeneBLAzer™ ADRA2A-Gqo5-NFAT-bla CHO-K1 cells (LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ ADRA2A-Gqo5-NFAT-bla CHO-K1 cells • GeneBLAzer™ ADRA2A-Gqo5-NFAT-bla CHO-K1 Assay Protocol • Certificate of Analysis
Storage: The GeneBLAzer™ ADRA2A-Gqo5-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.