Thermo Scientific™

Tango™ AGTRL1-bla U2OS Cells

Catalog number: K1754
Thermo Scientific™

Tango™ AGTRL1-bla U2OS Cells

Catalog number: K1754
Catalog Number
K1754
Unit Size
8 x 106 cells
Price (USD)
Price: 9,190.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K17548 x 106 cells
Price: 9,190.00
Your Price:
-
Product Overview
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The Tango™ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ AGTRL1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™AGTRL1-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NM_005161
Assay Entry
Cell-based beta-arrestin recruitment
Cell State
Dividing Cells
Cytoplasmic Tail
Native Tail
Detection Method
Fluorescent
Gene Symbol
AGTRL1
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Protein Family
GPCR (G-Protein Coupled Receptors)
Readout
End Point
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
AGTRL1
Cell Line
U2OS
System Type
Tango™
Druggable Target
GPCRs

Contents & Storage

K1754 Tango™ AGTRL1-bla U2OS cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ AGTRL1-bla U2OS cells
• Tango™ AGTRL1-bla U2OS Assay Protocol
• Certificate of Analysis
The Tango™ AGTRL1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.