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Thermo Scientific™

GeneBLAzer™ D5-CRE-bla CHO-K1 Cells

Catalog number:  K1784

Related applications:

Pharma & Biopharma

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Description

The GeneBLAzer® D5-CRE-bla CHO-K1 cells contain the human Dopamine Receptor 5 (D5) stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat. no. K1129) contain a beta-lactamase reporter gene under control of the CRE response element.

The GeneBLAzer® D5-CRE-bla CHO-K1 cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, GeneBLAzer® D5-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.

Specifications

Accession Number: NM_000676
Assay Entry: Cell-based beta lactamase reporter gene
Cell Line: CHO-K1
Cell State: Dividing Cells
Detection Method: Fluorescent
Druggable Target: GPCRs
Gene Symbol: DRD5
Population Status: Single Cell Clone Origin
Product Line: GeneBLAzer®
Protein Family: GPCR (G-Protein Coupled Receptors)
Readout: End Point
Reporter Gene: BLA (Beta-Lactamase)
System Type: GeneBLAzer™
Target Entry: DRD5, D5

Contents & storage

K1784 GeneBLAzer® D5-CRE-bla CHO-K1 cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer® D5-CRE-bla CHO-K1 cells
• GeneBLAzer® D5-CRE-bla CHO-K1 Assay Protocol
• Certificate of Analysis
The GeneBLAzer® D5-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.