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Tango™ CCR4-bla U2OS Cells

Catalog number:  K1799

 Related applications:

Pharma & Biopharma

| Target & Lead Identification & Validation

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The Tango™ CCR4-bla U2OS cells contain the human Chemokine (C-C Motif) Receptor 4 (CCR4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ CCR4-bla U2OS cells are functionally validated for Z' and EC50 concentrations of TARC. In addition, Tango™ CCR4-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
For Research Use Only. Not for use in diagnostic procedures.


Gene Symbol: CCR4
Accession Number: NM_005508
Cell Line: U2OS
Cell State: Dividing Cells
Cytoplasmic Tail: Native Tail
Detection Method: Fluorescent
Druggable Target: GPCRs
Population Status: Pool of Stable Cells
Product Line: GeneBLAzer®, Tango™
Product Size: 8 x 106 cells
Readout: End Point
Reporter: BLA (Beta-Lactamase)
System: Tango™
Technique: FRET
Shipping Condition: Room Temperature

Contents & storage

K1799 Tango™ CCR4-bla U2OS cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
• Tango™ CCR4-bla U2OS cells
• Tango™ CCR4-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ CCR4-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.


Manuals & protocols