During checkout, this product may be reported as "Out of Stock" with an Estimated Availability date. The Actual Availability date for this product may be earlier. Send inquiries regarding Actual Availability date, including the catalog number, to discoverysciences@lifetech.com.
Thermo Scientific™

T-REx™ Tango™ GHSR-bla U2OS Cells

Catalog number:  K1819

Related applications:

Pharma & Biopharma

Back to top


The T-REx™ Tango™ GHSR-bla U2OS cells contain the human Growth Hormone Secretagogue Receptor (GHSR) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The T-REx™ Tango™ GHSR-bla U2OS cells are functionally validated for Z' and EC50 concentrations of Ghrelin. In addition, T-REx™ Tango™ GHSR-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
For Research Use Only. Not for use in diagnostic procedures.


Accession Number: NM_198407
Assay Entry: Cell-based beta-arrestin recruitment
Cell Line: U2OS
Cell State: Dividing Cells
Cytoplasmic Tail: Tail from AVPR2 GPCR
Detection Method: Fluorescent
Druggable Target: GPCRs
Gene Symbol: GHSR
Human Protein Class: G-Protein Coupled Receptor (GPCR)
Population Status: Single Cell Clone Origin
Product Line: GeneBLAzer®, Tango™
Readout: End Point
System Type: Tango™
Target Entry: GHSR
Technique: FRET

Contents & storage

K1819 T-REx™ Tango™ GHSR-bla U2OS cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
• T-REx™ Tango™ GHSR-bla U2OS cells
• T-REx™ Tango™ GHSR-bla U2OS Assay Protocol
• Certificate of Analysis

The T-REx™ Tango™ GHSR-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.