GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 cells contain the human calcium-sensing receptor (CaSR), (Accession # NM_000388) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line. GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 (Cat. No. K1536) cells contain a beta-lactamase reporter gene under control of the NFAT Response Element.
The GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 cells are functionally validated for Z’-factor and EC50 concentrations of Spermine. In addition, GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions.
For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NM_000388
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
CaSR
Human Protein Class
G-Protein Coupled Receptor (GPCR)
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Readout
End Point
Target Entry
CASR
Type
CHO-K1 Cells
Cell Line
CHO-K1
System Type
GeneBLAzer™
Druggable Target
GPCRs
Contents & Storage
Contents: K1833 GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 cells (LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 cells • GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 Assay Protocol • Certificate of Analysis
Storage: The GeneBLAzer™ CaSR-Gqo5-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.