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Tango™ GPR120 (short)-bla U2OS cells contain the human GPR120 (short) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ GPR120 (short)-bla U2OS cells have been functionally validated for Z’ factor and EC50 concentrations of GW9508 (Figure 1). In addition, Tango™ GPR120 (short)-bla U2OS cells have been tested for assay performance under variable conditions.
For Research Use Only. Not for use in diagnostic procedures.
Cell-based beta-arrestin recruitment
For Use With (Application)
Human Protein Class
G-Protein Coupled Receptor (GPCR)
Single Cell Clone Origin
Contents & Storage
Note: LiveBLAzer™-FRET B/G Loading Kit, Solution D, and other materials are required separately—please refer to the protocol.