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Thermo Scientific™

GeneBLAzer™ PTGIR-CRE-bla CHO-K1 Cells

Catalog number:  K1850

Related applications:

Pharma & Biopharma

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Description

GeneBLAzer® PTGIR-CRE-bla CHO-K1 cells contain the human Prostaglandin I2 receptor (IP) (PTGIR), (Accession # NM_000960.3) stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the CRE Response Element. The GeneBLAzer® PTGIR-CRE-bla CHO-K1 cells are functionally validated for Z’-factor and EC50 concentrations of Iloprost (Figure 1). In addition, GeneBLAzer® PTGIR-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NM_000960.3
Assay Entry: Cell-based beta lactamase reporter gene
Cell Line: CHO-K1
Cell State: Dividing Cells
Detection Method: Fluorescent
Druggable Target: GPCRs
Gene Symbol: PTGIR
Human Protein Class: G-Protein Coupled Receptor (GPCR)
Population Status: Pool of Stable Cells
Product Line: GeneBLAzer®
Readout: End Point
System Type: GeneBLAzer™
Target Entry: PTGIR
Technique: FRET

Contents & storage

K1850 GeneBLAzer® PTGIR-CRE-bla CHO-K1 cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer® PTGIR-CRE-bla CHO-K1 cells
• GeneBLAzer® PTGIR-CRE-bla CHO-K1 Assay Protocol
• Certificate of Analysis
The GeneBLAzer® PTGIR-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.