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Thermo Scientific™

GeneBLAzer™ HTR2C-NFAT-bla CHO-K1 Cells

Catalog number:  K1877

Related applications:

Pharma & Biopharma

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Description

GeneBLAzer® HTR2C-NFAT-bla CHO-K1 cells contain the human 5-hydroxytrptamine (serotonin) receptor 2C (HTR2C), (Accession #NM_000868.1) stably integrated into the CellSensor® NFAT-bla CHO-K1 cell line. CellSensor® NFAT-bla CHO-K1 cells (Cat. no.K1078) contain a beta-lactamase reporter gene under control of the NFAT Response Element. The GeneBLAzer® HTR2C-NFAT-bla CHO-K1 cells are functionally validated for Z’-factor and EC50 concentrations of 5-Hydroxytrptamine. In addition, GeneBLAzer® HTR2C-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NM_000868.1
Assay Entry: Cell-based beta lactamase reporter gene
Cell Line: CHO-K1
Cell State: Dividing Cells
Detection Method: Fluorescent
Druggable Target: GPCRs
Human Protein Class: G-Protein Coupled Receptor (GPCR)
Population Status: Single Cell Clone Origin
Product Line: GeneBLAzer®
Readout: End Point
Reporter Gene: BLA (Beta-Lactamase)
System Type: GeneBLAzer™
Target Entry: HTR2C
Technique: FRET

Contents & storage

GeneBLAzer® cell lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.