RSV is the major cause of lower respiratory tract diseases in infants and young children causing seasonal epidemics of respiratory illness each year 1, 2.
Use IMAGEN Respiratory Syncytial Virus Kit as a rapid, sensitive and specific method for direct detection of RSV in clinical samples such as nasopharyngeal aspirates.
- Rapid results- within little over 30 minutes of receiving test sample or culture
- Simple- ready-to-use reagents plus all IMAGEN assays follow the same basic methodology
- Excellent sensitivity and specificity- high quality, well-characterized antibodies used in the assay provide excellent sensitivity and specificity
- Easy-to-read results
- Long Shelf Life- typically 24 months
RSV is an enveloped, spherical, RNA virus of the family paramyxoviridae and is classified in the genus Pneumovirus. This genus has four members: human RSV, bovine RSV, pneumonia virus of mice and turkey rhinotracheitis virus3, 4. RSV is spread by virus-laden droplets of respiratory secretions from infected individuals. Infection may manifest as a variety of symptoms, ranging from rhinitis to pneumonia, which are influenced by factors such as the age, sex and socio-economic background of infected individuals.5
The laboratory diagnosis of RSV plays an important role in patient management and assists in the control of outbreaks6, 7, 8,9, 10. Methods commonly employed for laboratory diagnosis of RSV infection include direct detection of virus or viral proteins in clinical samples such as nasopharyngeal aspirates and isolation of viable virus in cell culture monolayers inoculated with respiratory secretions11, 12
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Remel™ and Oxoid™ products are now part of the Thermo Scientific™ brand.
For In Vitro Diagnostic Use.
1.Respiratory syncytial virus: a community problem. British Medical Journal (1979) 2: 457-458.
2. Zaroukian M.H., Leader I. (1988) Community-acquired pneumonia and infection with respiratory syncytial virus. American Journal Medical Science 295:218-222.
3. Frankl R.I.B., Fauquet C.M., Knudson D.L., Brown F. (1992) Classification and Nomenclature of Viruses. Fifth Report of the International Committee on Taxonomy of Viruses. Archives of Virology Supplement 2, Spurger Velacy, New York, pp 245-246.
4. Gimenez H.B., Cash P., Melvin W.T. (1984) Monoclonal antibodies to human respiratory syncytial virus and their use in comparison of different virus isolates. Journal of General Virology 65: 963-971.
5. Hall W.J., Hall C.B., Speers D.M. (1978) Respiratory syncytial virus infection in adults. Clinical, virologic and serial pulmonary function studies. Annals of Internal Medicine 88: 203-205.
6. Ditchburn R.K., McQuillin J., Gardner P.S., Court S.D.M. (1971) Respiratory syncytial virus in hospital cross infection. British Medical Journal 3: 671-673.
7. Mintz, Ballard R.A., Sniderman S.H., Roth R.S., Drew W.L.(1979) Nosocomial respiratory syncytial virus infections in an intensive care nursery: rapid diagnosis by direct immunofluorescence. Pediatrics 64: 149-153.
8. Goldson E.J., McCarthy J.T., Welling M.A., Todd J.K. (1979) A respiratory syncytial virus outbreak in transitional care nursery. American Journal of Disease in Children 133: 1280-1282.
9. Hall C.B., Kopelman A.E., Douglas R G. Jnr., Geiman J.M.,Meagher M.P. (1979) Neonatal respiratory syncytial virus infection. New England Journal of Medicine 300: 393-396.
10. Gardner P.S., McQuillin J. (1980) Rapid virus diagnosis: Application of immunofluorescence (2ndEd.) Butterworth, London. pp 92-123.
11. Johnston S.L.G., Siegel C.S. (1990) Evaluation of direct immunofluorescence, enzyme immunoassay, centrifugation culture and conventional culture for the detection of respiratory syncytial virus. J. Clin. Microbiol 28: 2394-2397.
12. McQuillin J., Gardner P.S., (1968) Rapid diagnosis of respiratory syncytial virus infection by immunofluorescent antibody techniques. British Medical Journal 1: 602-605.