4-(2-Hydroxyethyl)pyridine, 98%

Name: 4-(2-Hydroxyethyl)pyridine, 98%
SKU: L13780.03

CAS: 5344-27-4 | C7H9NO | 123.155 g/mol

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Catalog number L13780.03

also known as L13780-03

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Chemical Identifiers

CAS5344-27-4

IUPAC Name2-(pyridin-4-yl)ethan-1-ol

Molecular FormulaC7H9NO

InChI KeyDWPYQDGDWBKJQL-UHFFFAOYSA-N

SMILESOCCC1=CC=NC=C1

Specifications

Specification Sheet

Appearance (Color)Clear colorless to yellow to green

FormLiquid or viscous liquid

Refractive Index1.5365-1.5410 @ 20°C

Assay (GC)≥97.5%

4-(2-Hydroxyethyl)pyridine acts as a reagent for the protection of carboxyl groups as their 2-(4-pyridyl)ethyl esters in organic synthesis. Further, it is used as an active pharmaceutical ingredient intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-(2-Hydroxyethyl)pyridine acts as a reagent for the protection of carboxyl groups as their 2-(4-pyridyl)ethyl esters in organic synthesis. Further, it is used as an active pharmaceutical ingredient intermediate.

Solubility
Miscible with water.

Notes
Hygroscopic. Moisture sensitive. Incompatible with strong oxidizing agents, bases and mineral acids.

RUO – Research Use Only

General References:

Reagent for protection of carboxyl groups as their 2-(4-pyridyl)ethyl esters, by reaction with the acid chloride: Tetrahedron Lett., 25, 1223 (1984). See preceding entry under 2-isomer. See also 4-Vinyl pyridine, L13316.
Kato, Y.; Kawasaki, M.; Nigo, T.; Nakamura, S.; Fusano, A.; Teranishi, Y.; Ito, M. N.; Sumiyoshi, T. Identification of 2,3-disubstituted pyridines as potent, orally active PDE4 inhibitors. Bioorg. Med. Chem. 2013, 21 (18), 5851-5854.
Aschenbrücker, J.; Steegmüller, U.; Ernsting, N. P.; Buback, M.; Schroeder, J.; Jasny, J. Picosecond UV pump/IR probe spectrometer for the 2-5 mum spectral region. Appl. Phys. B: Lasers Opt. 1997, 65 (4), 441-444.