Search Thermo Fisher Scientific
Element Search
Structure Search
Thermo Scientific Chemicals
Isopentyl nitrite, 97%, stab. with 0.2% anhyd. sodium carbonate, Thermo Scientific Chemicals
Have Questions?
Change view
Catalog number L13909.AP
also known as L13909-AP
Price (USD)/ Each
138.65
Online exclusive
163.00 Save 24.35 (15%)
-
Quantity:
500 mL
Price (USD)/ Each
138.65
Online exclusive
163.00 Save 24.35 (15%)
Isopentyl nitrite, 97%, stab. with 0.2% anhyd. sodium carbonate, Thermo Scientific Chemicals
Catalog numberL13909.AP
Price (USD)/ Each
138.65
Online exclusive
163.00 Save 24.35 (15%)
-
Chemical Identifiers
IUPAC Name3-methylbutyl nitrite
Molecular FormulaC5H11NO2
InChI KeyOWFXIOWLTKNBAP-UHFFFAOYSA-N
SMILESCC(C)CCON=O
Molecular Weight (g/mol)117.15
View more
Specifications
Specification Sheet
Specification SheetIdentification (FTIR)Conforms
Refractive Index1.3845-1.3895 @20?C
Appearance (Color)Clear colorless to yellow or pale orange
Assay (GC)≥96.0%
FormLiquid
Isopentyl nitrite is used in the conversion of 2,6-disubstituted phenols to diphenoquinones and aminophenols to quinone diazides. It acts as an oxidant and nitrosating agent. It finds application in aromatic arylation, deamination of arylamines using tetrahydrofuran as a hydrogen donor. It is also useful for the preparation of benzyne using anthranilic acid. It is an antihypertensive and vasodilator to treat heart diseases such as angina and an antidote for cyanide poisoning. Further, it is used as a solvent and cleaning agent for a printed circuit board. In addition to this, it is considered to be a replacement for freon.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Miscible with methanol, chloroform and ether. Slightly miscible with water.
Notes
Air, moisture and light sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents and alcohol.
Miscible with methanol, chloroform and ether. Slightly miscible with water.
Notes
Air, moisture and light sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents and alcohol.
RUO – Research Use Only
General References:
- Widely used in non-aqueous nitrosation and diazotization reactions.
- For aromatic arylation as an alternative to the Gomberg reaction, see: J. Chem. Soc., 4257 (1962). For deamination of arylamines using THF as a hydrogen donor, see: J. Chem. Soc., Perkin 1, 541 (1973).
- For use in the generation of benzyne from anthranilic acid, see: J. Org. Chem., 38, 3462 (1973).
- ɑ-Amino esters are converted to ɑ-diazo esters: Tetrahedron, 31, 227 (1975).
- For other reactions of alkyl nitrites, see Isobutyl nitrite, L05259 , and tert-Butyl nitrite, L16135 .
- Liu, Z.; Zhu, S.; Li, Y.; Li, Y.; Shi, P.; Huang, Z.; Huang, X. Preparation of graphene/poly(2-hydroxyethyl acrylate) nanohybrid materials via an ambient temperature grafting-from strategy. Polym. Chem. 2015, 6 (2), 311-321.
- Wang, Y.; Meng, L.; Fan, L.; Wu, G.; Ma, L.; Huang, Y. Preparation and properties of carbon nanotube/carbon fiber hybrid reinforcement by a two-step aryl diazonium reaction. RSC Adv. 2015, 5 (55), 44492-44498.