A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Aplicaciones
Es un nuevo derivado de 1-fenil-2-pirrolidinona, blebistatina, que inhibe la actividad de la miocina II no muscular con alta especificidad.
Solubilidad
Soluble en cloroformo y acetato de etilo. Insoluble en agua.
Notas
Almacenar en fresco. Mantener el recipiente bien cerrado en un lugar seco y bien ventilado. Almacenar alejado de agentes oxidantes.
RUO – Research Use Only
General References:
- Mark S Duxbury; Stanley W Ashley; Edward E Whang. Inhibition of pancreatic adenocarcinoma cellular invasiveness by blebbistatin: a novel myosin II inhibitor. Biochemical and Biophysical Research Communications.2004, 313(4), 992-997.
- John S Allingham; Robert Smith; & Ivan Rayment. The structural basis of blebbistatin inhibition and specificity for myosin II. Nature Structural & Molecular Biology.2005, 12378 - 379.