LysoSensor Yellow/Blue dextran is a ratiometric probe that can be used to measure the pH of acidic organelles, such as lysosomes. This dextran conjugate is taken up by the cells through endocytosis. The LysoSensor dye produces blue fluorescence in neutral environments, but changes to yellow fluorescence in more acidic environments. The pKa of LysoSensor Yellow/Blue dextran is ∼3.9.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Color
Yellow, Blue
Detection Method
Fluorescent
Emission
335⁄452
Product Line
LysoSensor™
Shipping Condition
Room Temperature
Sub Cellular Localization
Lysosomes
For Use With (Equipment)
Fluorescence Microscope
Contents & Storage
Store in freezer -5°C to -30°C and protect from light.
Figures
Dual-emission ratiometric measurement of lysosomal pH using LysoSensor™ Yellow/Blue dextran.
