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Citas y referencias (42)
Invitrogen™
LDS 751
LDS 751 es un colorante de ácidos nucleicos que penetra en la célula con un pico de excitación a ∼Más información
| Número de catálogo | Cantidad |
|---|---|
| L7595 | 10 mg |
Número de catálogo L7595
Precio (MXN)
-
Cantidad:
10 mg
LDS 751 es un colorante de ácidos nucleicos que penetra en la célula con un pico de excitación a ∼ 543 nm en ADNbc y es particularmente útil en análisis multicolor gracias a su emisión de longitud de onda larga máxima (∼ 712 nm). La unión de LDS 751 al ADNbc tiene como resultado un aumento de la fluorescencia de ∼ 20 veces.
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
Especificaciones
Método de detecciónFluorescente
Tipo de coloranteLDS 751
Intervalo de longitud de onda de excitación543⁄712
Para utilizar con (equipo)Citómetro de flujo
FormularioSólido
Cantidad10 mg
Condiciones de envíoTemperatura ambiente
Tipo de productoLDS 751
SubCellular LocalizationNucleicos, ácidos nucleicos, Nucleus
Unit SizeEach
Contenido y almacenamiento
Contiene 1 vial de LDS 751 (10 mg). Almacenar a temperatura ambiente y proteger de la luz.
Citations & References (42)
Citations & References
Abstract
Dyes providing increased sensitivity in flow-cytometric dye-efflux assays for multidrug resistance.
Journal:Cytometry
PubMed ID:7587707
In an effort to improve detection of P-glycoprotein-mediated multidrug resistance (mdr), several dyes were compared to rhodamine 123 (R123) in efflux assays. Two dyes (SY-38 and SY-3150) were found that provided better sensitivity. These dyes were effluxed by a cell line known to be mdr-positive (P388/R84) but not by an
Modulation of platelet-neutrophil interaction with pharmacological inhibition of fibrinogen binding to platelet GPIIb/IIIa receptor.
Journal:Thromb Haemost
PubMed ID:10064007
'The study investigated how drug inhibition of the GPIIb/IIIa receptor influences the interactions between platelets and leukocytes. These interactions are believed to play an important role in the etiology of the acute coronary syndromes. Thirty patients with unstable angina or non-Q-wave myocardial infarction were studied before the administration of tirofiban
Discriminating between damaged and intact cells in fixed flow cytometric samples.
Journal:Cytometry
PubMed ID:2460298
'A vital, nucleic acid stain (LDS-751) was used to discriminate intact from damaged cells in a flow cytometer even after the samples had been fixed with paraformaldehyde. Three major cell populations with different fluorescence properties with LDS-751 were found in the fixed samples. Cells not staining or only dimly staining
The Q-Prep system: effects on the apparent expression of leucocyte cell surface antigens.
Journal:Cytometry
PubMed ID:9149913
'To facilitate the analysis of immunolabelled peripheral blood or bone marrow leucocytes by flow cytometry, a number of reagents are available commercially that lyse erythrocytes and fix leucocytes. This study has investigated the effect on antibody-labelled whole blood of the Q-Prep procedure, in which erythrocytes are lysed with formic acid,
Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs.
Journal:Biochemistry
PubMed ID:16229491
'The P-glycoprotein efflux pump, an ABC superfamily member, can export a wide variety of hydrophobic drugs, natural products, and peptides from cells, powered by the energy of ATP hydrolysis. Transport substrates appear to first partition into the membrane and then interact with the protein within the cytoplasmic leaflet. Two drug