Search

  • Order Status
  • Quick Order
  • Promos

Invitrogen

WNT5A Recombinant Rabbit Monoclonal Antibody (23GB2400)

Advanced Verification
View all (24) WNT5A antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Datasheet
Certificates
Protocols
Questions & Answers
Datasheet
Certificates
Protocols
Questions & Answers
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
WNT5A Recombinant Rabbit Monoclonal Antibody (23GB2400)

Product Details

MA5-53582

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

Immunocytochemistry (ICC/IF)

1:100-1:1,000
-

Flow Cytometry (Flow)

1:200-1:2,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

23GB2400

Immunogen

A synthesized peptide derived from human Wnt5a (330-360AA).
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Amount

40 µg

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3248053

Target Information

Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: epididymis secretory sperm binding protein; hWNT5A; OTTHUMP00000212837; OTTHUMP00000212861; unnamed protein product; wingless-type MMTV integration site family, member 5A; WNT-5A protein

View more View less

Gene Aliases: hWNT5A

View more View less

UniProt ID: (Human) P41221

View more View less

Entrez Gene ID: (Human) 7474

View more View less

Function(s)
receptor binding frizzled binding receptor tyrosine kinase-like orphan receptor binding cytokine activity protein binding phospholipid binding protein domain specific binding receptor agonist activity chemoattractant activity involved in axon guidance
Process(es)
epithelial to mesenchymal transition positive regulation of endothelial cell proliferation lens development in camera-type eye positive regulation of cytokine production involved in immune response primary heart field specification secondary heart field specification ventricular septum development atrial septum development optic cup formation involved in camera-type eye development inflammatory response phospholipase C-activating G-protein coupled receptor signaling pathway Wnt signaling pathway, calcium modulating pathway axonogenesis axon guidance protein localization male gonad development anterior/posterior axis specification, embryo positive regulation of endothelial cell migration positive regulation of gene expression macrophage derived foam cell differentiation positive regulation of T cell chemotaxis positive regulation of neuron projection development Wnt signaling pathway olfactory bulb interneuron development neurogenesis neuron differentiation keratinocyte differentiation midbrain development positive regulation of chemokine production positive regulation of interferon-gamma production positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of Rac protein signal transduction non-canonical Wnt signaling pathway chemoattraction of serotonergic neuron axon chemorepulsion of dopaminergic neuron axon wound healing positive regulation of macrophage activation negative regulation of apoptotic process regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of MAPK cascade cell fate commitment negative regulation of fat cell differentiation positive regulation of protein catabolic process positive regulation of angiogenesis positive regulation of ossification negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade negative regulation of melanin biosynthetic process positive regulation of fibroblast proliferation embryonic skeletal system development genitalia development neuron projection morphogenesis regulation of inflammatory response positive regulation of inflammatory response regulation of synapse organization positive regulation of small GTPase mediated signal transduction positive regulation of anagen positive regulation of protein kinase B signaling negative regulation of synapse assembly canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway face development positive regulation of type I interferon-mediated signaling pathway positive regulation of response to cytokine stimulus positive regulation of macrophage cytokine production secondary palate development cellular response to molecule of bacterial origin cellular response to lipopolysaccharide cellular response to calcium ion cellular response to retinoic acid cellular response to interferon-gamma hematopoietic stem cell proliferation dopaminergic neuron differentiation cellular response to transforming growth factor beta stimulus negative regulation of mesenchymal cell proliferation negative regulation of canonical Wnt signaling pathway melanocyte proliferation presynapse assembly postsynapse assembly postsynaptic modulation of chemical synaptic transmission regulation of postsynapse organization regulation of postsynaptic cytosolic calcium ion concentration positive regulation of neuron projection arborization positive regulation of protein kinase C activity positive regulation of protein localization to synapse excitatory synapse assembly inhibitory synapse assembly negative regulation of cell proliferation in midbrain midbrain dopaminergic neuron differentiation positive regulation of non-canonical Wnt signaling pathway positive regulation of apoptotic signaling pathway
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support