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Invitrogen
DGKZ Monoclonal Antibody (K49027_10E9)
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FIGURE: 1 / 3
DGKZ Antibody (MA5-55687) in IHC (P)
Immunohistochemistry analysis of DGKZ in paraffin-embedded cerebellum tissue. Sample was incubated with DGKZ monoclonal antibody (Product # MA5-55687) at a dilution of 5 µg/mL (RT, 1 hour). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% H2O2 for 30 min at room temperature. ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-55687
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
K49027_10E9
Immunogen
Recombinant human DGKZ (immunogen range is 832-921).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
Product Specific Information
Sequence of this protein is as follows: STGSKDVVRY LLDHAPPEIL DAVEENGETC LHQAAALGQR TICHYIVEAG ASLMKTDQQG DTPRQRAEKA QDTELAAYLE NRQHYQMIQR
Target Information
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DAG kinase DAGK6; DAG kinase zeta; DGK-zeta; diacylglycerol kinase, zeta 104kDa; Diglyceride kinase; diglyceride kinase zeta; protein kinase; unnamed protein product
Gene Aliases: DAGK5; DAGK6; DGK-ZETA; E130307B02Rik; F730209L11Rik; hDGKzeta; mDGK[z]
UniProt ID: (Human) Q13574, (Mouse) Q80UP3
Entrez Gene ID: (Human) 8525, (Mouse) 104418
phosphatidic acid biosynthetic process
signal transduction
phospholipase C-activating G-protein coupled receptor signaling pathway
mitotic G1 DNA damage checkpoint
intracellular signal transduction
diacylglycerol metabolic process
glycerolipid metabolic process
regulation of Ras protein signal transduction
negative regulation of Ras protein signal transduction
lipid phosphorylation
negative regulation of T cell receptor signaling pathway
maintenance of postsynaptic density structure
cell migration
platelet activation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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