Thermo Scientific™

CD15, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Obtain accurate and reproducible results in immunohistochemistry applications with Thermo Scientific™ CD15, Mouse Monoclonal Antibody, one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.

 

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CD15 or X-hapten plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Host Species: Mouse

Clone: SPM490

Isotype: IgM

Species Reactivity: Human. Others not tested.

Epitope: Not known

Immunogen: K562 (an erythroid-myeloid leukemia cell line)

Molecular Weight: 220kDa

Positive Control: Reed-Sternberg's cells in Hodgkin's lymphoma

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)