DP-1 Transcription Factor Ab-6, Mouse Monoclonal Antibody

Thermo Scientific™  Related applications: Anatomical Pathology

Ensure accurate, reproducible results in western blotting experiments with Thermo Scientific™ DP-1 Transcription Factor Ab-6, Mouse Monoclonal Antibody.

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Description

DP family contains at least two members, DP-1 and -2. Structurally, DP-1 and -2 are relatively conserved, yet their expression appears to be tissue specific. E2F-1, a functional target for the tumor suppressor protein Rb, heterodimers with DP-1 and forms an active E2F transcriptional complex. The interaction between members of the E2F and the DP families is mediated, in part, by a leucine repeat which is weakly conserved between the two families.

Host Species: Mouse

Clone: 1DP06 (TFD10)

Isotype: IgG1/κ

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 83-204

Immunogen: Recombinant DP-1 protein

Molecular Weight: 45 kDa

Positive Control: MAD109 or Raji cells, Tonsil

Cellular Localization: Cytoplasm and nucleus

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO

General References:

1. Adams, P. D., and W. G. Kaelin Jr. 1996. p. 79-95. In P. J. Farnham (ed.), Transcriptional control of cell growth: the E2F gene family, vol. 208. Springer, Berlin Heidelberg.

2. 'Asken, D. S., et al.. (1991)Oncogene. 6:1915-1922.



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