|Catalog number||Product Size||Formulation||Quantity||Price (USD)|
|MS-138-P||'>-||'>Purified Ab with BSA and Azide||'>1mL|
|MS-138-P0||'>-||'>Purified Ab with BSA and Azide||'>100μL|
|MS-138-P1||'>-||'>Purified Ab with BSA and Azide||'>500μL|
|MS-138-P1ABX||'>-||'>Ab without BSA/Azide (Frozen)||'>100μL|
|MS-138-PABX||'>-||'>Ab without BSA/Azide (Frozen)||'>200μL|
|MS-138-R7||'>-||'>Ready-to-use for IHC (UVLP)||'>7mL|
Tumor-associated glycoprotein (TAG-72) is an oncofetal antigen with properties of a mucin. About 60% of carcinoma patients express TAG-72 in their sera.
Host Species: Mouse
Species Reactivity: Human, Cow, Dog, Hamster and Rat. Others not known.
Epitope: Mucin-carried-sialylated-Tn epitope
Immunogen: Membrane-enriched fraction of a human breast carcinoma liver metastasis
Molecular Weight: >1000kDa
Positive Control: Breast or lung CA
Cellular Localization: Cell surface and cytoplasmic. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for Ab-1 staining. Weak or no reactivity has been observed with most cell types of normal adult tissue excepting the secretory endometrium. Ab-1 is reportedly useful in distinguishing pulmonary adenocarcinomas (B72.3+) from pleural mesotheliomas (B72.3-).
USA: RUO; Int'l: RUO
1. Brown RW et al. Human Pathol, 1993, 24:347-54.
2. Myers RB et al. J Urol, 1994, 152(1):243-6.
3. Roa RA et al. Laryngoscope, 1994, 104:304-8.