Thermo Scientific™

Lab Vision™ CD1a Ab-5, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Obtain accurate, reproducible results in immunohistochemistry applications with Thermo Scientific™ CD1a Ab-5, Mouse Monoclonal Antibody.
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At least five CD1 genes (CD1a, b, c, d, and e) have been identified. CD1 is expressed on cortical thymocytes, Langerhans cells, and dendritic cells. It is absent on mature peripheral blood T cells but intracytoplasmic expression is detected on activated T lymphocytes. CD1 proteins have been demonstrated to restrict T-cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation.

Host Species: Mouse

Clone: O10

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Molecular Weight: 49kDa

Positive Control: Tonsil

Cellular Localization: Membrane and cytoplasm

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

General References:

1. Bobryshev Y V, et al. Pathol Res Pract. 192: 462-467 (1996).

2. Aractingi S, et al. J Clin Pathol. 50: 305-309 (1997).

3. Mazal P R, et al Clin Neuropathol. 15: 87-91 (1996).