Thermo Scientific™

Lab Vision™ Mammaglobin, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Employ one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available with the Thermo Scientific™ Mammaglobin, Mouse Monoclonal Antibody.
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Mammaglobin, a member of the uteroglobin family, is a 10kDa glycoprotein. Mammaglobin mRNA expression is breast tissue specific. It is overexpressed in human breast cancer. The use of Mammaglobin RT-PCR has been demonstrated to detect disseminated breast cancer. In a study to evaluate the frequency and specificity of mammaglobin, 80% of all primary and metastatic breast tumors tested were immunopositive irrespective of tumor grade, while mammaglobin mRNA was detected in 60% of the peripheral stem cell collections from breast cancer patients.

Host Species: Mouse

Clone: 304-1A5

Isotype: IgG1

Species Reactivity: Human. Others not tested.

Immunogen: Recombinant full-length protein

Molecular Weight: 10kDa

Positive Control: Breast carcinoma

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

General References:

1. Fleming TP and MA Watson. Ann N Y Acad Sci. 2000 923: 78-89

2. Marchetti A et al. J. Pathol. 2001 195(2): 186-90

3. Watson MA et al. Can. res. 1999 59: 3028-3031