Thermo Scientific™

Lab Vision™ S100 Protein Ab-1, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Provide accurate, reproducible results with the Thermo Scientific™ S100 Protein Ab-1, Mouse Monoclonal Antibody.
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S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.

Host Species: Mouse

Clone: 4C4.9

Isotype: IgG2a

Species Reactivity: Human, Cow, Rat and Mouse. Others not known.

Epitope: Not determined

Immunogen: Purified bovine brain S100 protein

Molecular Weight: ∽22kDa (nonreduced); ∽11kDa (reduced)

Positive Control: Melanoma or Schwannoma

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

General References:

1. McLaren KM et al. Human Pathology, 1996 Jul, 27(7):633-6.

2. Joshi MG et al. Modern Pathology, 1996 Jan, 9(1):57-62.