Thermo Scientific™

Lab Vision™ Progesterone Receptor Ab-8, Mouse Monoclonal Antibody

 Related applications:
Anatomical Pathology
Provide accurate, reproducible results with the Thermo Scientific™ Progesterone Receptor Ab-8, Mouse Monoclonal Antibody.

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Human PgR exists in two forms: 116kDa (B-form) and 81kDa (A-form). It acts as ligand activated transcription factor to regulate expression of the target genes. Null mutation in PgR gene leads to pleiotrophic reproductive abnormalities.

Host Species: Mouse

Clone: hPRa 2 + hPRa 3

Isotype: IgG1/κ + IgG1/κ

Species Reactivity: Human, Horse, Sheep and Pig. Others not known.

Epitope: N-terminal half of human PgR

Immunogen: PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice

Molecular Weight: 116kDa (B-form) and 81kDa (A-form)

Positive Control: T47D or Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Sedimentation in Sucrose Gradient
General References:

1. Clarke CL et. al. Endocrinology, 1987, 121:1123-32.

2. Gray GO Satyaswaroop PG. Biochem Biophys Res Comm, 1988, 157(3):1067-77.


Manuals & protocols