Thermo Scientific™

Lab Vision™ CD35/CR1 (Follicular Dendritic Cell Marker), Mouse Monoclonal Antibody

 Related applications:
Anatomical Pathology
Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence and flow cytometry experiments with Thermo Scientific™ CD35/CR1 (Follicular Dendritic Cell Marker), Mouse Monoclonal Antibody.

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Description

Complement receptor 1 (CR1, CD35) is a cell membrane-bound, monomeric glycoprotein that is found on numerous cell types of primates including erythrocytes, lymphocytes, and phagocytes. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules.

Host Species: Mouse

Clone: E11

Isotype: IgG1

Species Reactivity: Human, Rhesus Monkey and Baboon. Others not tested.

Epitope: Distal from the C3b-binding site

Immunogen: Intact human monocytes

Molecular Weight: 210-220 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

General References:

1. Hogg N, et. al. Eur Journal of Immunology, 1984, 14:236-43.

2. Leucocyte Typing III (1987). Ed by A. J. Mc Michael et. al.

3. Hogg N, et. al. 91984) Blood 63:566-573.



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