Thermo Scientific™

Lab Vision™ Cytokeratin 20 Ab-1, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Thermo Scientific™ Cytokeratin 20 Ab-1, Mouse Monoclonal Antibody.
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Keratin 20/cytokeratin20 (CK20) is a Type-I keratin which is primarily expressed in gastric and intestinal epithelium, urothelium, and Merkel-cells. CK20 is expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system. CK20 is also present in mucinous ovarian tumors, transitional-cell and Merkel-cell carcinomas. Notably, the squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas lack in CK20.

Host Species: Mouse

Clone: Ks20.8

Isotype: IgG2a

Species Reactivity: Human and Mouse. Does not react with rat. Others not known.

Epitope: Not determined

Immunogen: Semi-purified human cytokeratin preparation

Molecular Weight: 46 kDa

Positive Control: HT29 cells, Colon CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

General References:

1. Moll R et al. Am J of Pathology, 1992, 140:427-47.

2. Moll R et al. Am J of Pathology, 1992, 140:427-47.

3. Moll R et al. J of Cell Biol, 1990, 111:567-80.

4. Moll R et al. Differentiation, 1993, 53:75-93.

5. Moll R et al. Differentiation, 1993, 53:75-93.

6. Moll R et al. J of Cell Biol, 1990, 111:567-80.