Dystrophin Ab-1, Mouse Monoclonal Antibody

Thermo Scientific™  Related applications: Anatomical Pathology

Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence, affinity purification and electron microscopy applications with Thermo Scientific™ Dystrophin Ab-1, Mouse Monoclonal Antibody.

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Description

Dystrophin is a member of the spectrin/α-actinin family of actin-binding, triple helix rod-containing proteins. It is absent or greatly reduced in individuals with the X-linked recessive Duchenne's muscular dystrophy disorder, as well as in mice with the mdx (murine muscular dystrophy) mutation.

Host Species: Mouse

Clone: 1808

Isotype: IgG1

Species Reactivity: Human, Mouse, Rat, Chicken, Xenopus and Torpedo. Others not known.

Epitope: Not determined

Immunogen: Acetylcholine receptor (AChR)-enriched membranes and peripheral membrane proteins from Torpedo nobiliana electric organ

Molecular Weight: 427 kDa

Positive Control: Skeletal muscle

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence
  • Affinity Purification
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

General References:

1. Sealock R, et. al. J Cell Biol, 1991, 113:1133-44.



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