Host Species: Mouse
Species Reactivity: Human, Chinese Hamster. Does not react with mouse. Others not known.
Epitope: Extracellular amino terminal half. This epitope is resistant to formalin fixation and periodate oxidation and is different from those of other commonly known MAbs to p-glycoprotein, such as C219, JSB-1, and MRK16, which recognize an intracellular and extracellular epitope of p-glycoprotein, respectively.
Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes
Molecular Weight: 170kDa
Positive Control: Drug-resistant cells, Kidney or breast CA
Cellular Localization: Membrane
USA: RUO; Int'l: RUO
1. Chu TM, et. al. Hybridoma, 1993, 12(4):417-29.
2. Chu TM, et. al. Biochemical and Biophysical Research Communications, 1994, 203:506-12.