Thermo Scientific™

Lab Vision™ Bax Ab-1, Mouse Monoclonal Antibody

 Related applications:
Anatomical Pathology
Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, and flow cytometry experiments with Thermo Scientific™ Bax Ab-1, Mouse Monoclonal Antibody.

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Description

Bcl-2, Bax, and Bcl-X are members of a family of proteins that regulate apoptosis. In contrast to Bcl-2α and Bcl-XL, overexpression of bax protein accelerates the programmed cell death (apoptosis).

Host Species: Mouse

Clone: 2D2

Isotype: IgG1/κ

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: aa 3-16

Immunogen: A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human Bax protein. This amino acid sequence is not shared by mouse and rat Bax protein.

Molecular Weight: 21kDa

Positive Control: HeLa cells, Hodgkin's lymphoma

Cellular Localization: Cytoplasmic and cell membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Flow Cytometry (Not tested)

Note:

USA: RUO; Int'l: RUO

General References:

1. Hsu YT, et. al. J Bio Chem, 1997, 272(21):13829-34.

2. Hsu YT, et. al. PNAS USA, 1997, 94(8):3668-72.



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