Thermo Scientific™

Lab Vision™ CD10/CALLA (Neutral Endopeptidase) Ab-2, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Obtain accurate, reproducible results in Immunohistochemistry experiments with Thermo Scientific™ CD10/CALLA (Neutral Endopeptidase) Ab-2, Mouse Monoclonal Antibody, one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.

Back to top
CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Host Species: Mouse

Clone: 56C6

Isotype: IgG1

Species Reactivity: Human and Rat. Others not tested.

Epitope: Extracellular

Immunogen: Recombinant external domain of CD10 protein

Molecular Weight: 100kDa

Positive Control: Small intestine

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

General References:

1. Guerin S et al. Faseb Journal, 1997 Apr, 11(5):376-81.

2. Guerin S et al. Cellular Immunology, 1997 Jan 10, 175(1):85-91.