Thermo Scientific™

MMP-9 (92kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Supply accurate, reproducible results with the Thermo Scientific™ MMP-9 (92kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody.
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MMPs are a group of enzymes involved in matrix degradation. They share some important characteristics, such as a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and inhibition by specific proteinase inhibitors known as tissue inhibitors of metalloproteinases (TIMPs). Reportedly, MMPs play a crucial role in tumor cell invasion and metastasis.

Host Species: Mouse

Clone: IA5

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human native 92kDa MMP-9

Molecular Weight: 92kDa (proform) and ∽86kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) human fibrosarcoma HT-1080 cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Not suitable)

Note:

USA: RUO; Int'l: RUO

General References:

1. Paquet P, et al. Eur J Clin Invest 199828:528-532.

2. Jackson CJ, et al. Int J Biochem Cell Biol 199729(10):1167-1177.