NanoDrop™ One/One^C Microvolume UV-Vis Spectrophotometer

Move one step closer to your research goals with an ergonomic, standalone spectrophotometer with high-resolution, touch screen interface. Powerful auto-range pathlength technology facilitates accurate measurements for concentrated samples with no need for dilutions. This is your innovative alternative to the NanoDrop 2000/2000c Spectrophotometers.

NanoDrop One/Nanodrop One^C PC Software with 21 CFR Part 11 Compliance

• New PC Control software allows users to control the instrument from an Ethernet connected PC - free download here 
• Optional Thermo Scientific Security Suite for NanoDrop One/One^C allows the instrument to be used in a 21 CFR Part 11 compliant lab. Features include:
  • User account access
  • Audit trail
  • Electronic signatures
  • Automated data back-up, and more

Acclaro Sample Intelligence Technology

• Acclaro technology enhances user understanding of sample quality while delivering accurate quantitative measurements. Early identification of contaminants can prevent failure of downstream applications and save days of troubleshooting.
• Verify sample quality in seconds - identify sample contaminants and obtain corrected concentration results.
• Access information through alerts – receive instant feedback about sample quality with on-demand technical support and guided troubleshooting.
• Rely on accurate results – ensure measurement integrity with embedded sensor and digital image analysis.

NanoDrop One/NanoDrop One^C Enhancements

• Ergonomic, standalone design – integrated Android™ tablet eliminates the need for a separate computer and provides seamless data transfer via Wireless*, Ethernet or USB.
• Auto-Measure and Auto-Blank functions – multi-sample processing can be streamlined with instant measurements that occur when the pedestal arm is down. These functions can be turned ON or OFF with a single tap on the screen.
• Wider dynamic range – no dilutions required for highly concentrated samples (dsDNA at 27,500 ng/µL) with auto-range pathlength technology
• Integrated Learning Center - an archive of technical support documents and educational animations at your fingertips.

Advanced Connectivity for Data Storage, Printing and Sharing

• Multiple choices for data export: transfer results with a USB, Wi-Fi or Ethernet connection to your PC or save data directly to the Thermo Fisher Cloud via Wi-Fi or Ethernet network.
• View, organize and share data on a PC: Once exported, you can view the full-data formats (e.g., contaminant analysis spectral graphs) and organize experiments using the NanoDrop One/One^C PC Control software.
• Easy data-to-printer options: Print your results directly from the NanoDrop One instrument via Wi-Fi, Ethernet or USB printer connection; print exported data from your PC using the Nanodrop One/One^C PC Control software.
• 24/7 access to data: View data anytime, anywhere from any device (Android-based or iOS-based devices, PC or Mac desktop computers) when you collect, analyze, store and share your NanoDrop One data on the NanoDrop App found on the [https://www.thermofisher.com/us/en/home/cloud.html] Thermo Fisher Cloud. Requires registration.
• Online collaborations: Share data between colleagues who do not have an instrument and view NanoDrop One data across multiple Thermo Fisher Cloud-connected accounts.

NanoDrop One^C Highlights

• Contains both pedestal and cuvette positions to expand experimental flexibility and increase the dynamic range.
• Measure dilute samples, perform kinetics experiments and take optical density measurements of bacterial cultures.
• Cuvette position includes temperature control and stirring.

NanoDrop One/NanoDrop One^C Capabilities

• Wide spectral range (190-850 nm) for measuring a variety of samples types:
  • Peptides (205 nm)
  • DNA and RNA (260 nm)
  • Purified protein (280 nm)
  • Toxicology assays and industrial dyes (490 nm)
  • Gold nanoparticles (520 nm)
  • Colorimetric protein assays (BCA 562 nm, Bradford 595 nm, Modified Lowry 650 nm, Pierce 660 660 nm)
  • Optical Density measurements (600 nm)
• Combining the patented** sample-retention system with cuvette capability accommodates low and high concentrations (2.0 - 27,500 ng/µL dsDNA and 0.06 - 820 mg/mL BSA)
• Pedestal measurements that require only 1 – 2 µL of your sample and do not require sample dilution, even for highly concentrated samples
• Calculates sample purity ratios (A260/A280 nm and A260/A230 nm)
• Pre-configured methods for DNA, Protein A280, Microarray, Protein and Labels, Pierce 660, Bradford, BCA, and Lowry
• User-friendly software includes custom methods and data export capabilities

* Wi-Fi model not available in certain countries – consult your local NanoDrop distributor

**Patents US6628382 and US6809826

For research use only; not for diagnostic purposes.