NanoDrop Ultra Microvolume UV-Vis Spectrophotometers and Fluorometers

The Thermo Scientific™ NanoDrop™ Ultra Spectrophotometers and Fluorometers represent the next generation of microvolume detection. These cutting-edge instruments deliver exceptional accuracy and sensitivity for nucleic acid and protein analysis with sample volumes as low as 1.0 μL. The NanoDrop Ultra is designed to streamline workflows across a wide range of fields, including genomics, proteomics, molecular biology, biotechnology, pharmaceutical, and life sciences research. It provides unparalleled precision, efficiency, and reliability in one compact device.

Avoid costly setbacks in your workflow with an understanding of sample quality like never before using the Thermo Scientific™ NanoDrop™ Ultra Microvolume UV-Vis Spectrophotometers Fluorometers. Innovative Thermo Scientific™ Acclaro™ Sample Intelligence technology is built into every instrument for improved measurement accuracy and contaminant identification. Quantify and qualify DNA, RNA, and protein samples in seconds with only 1-2μL, and obtain full-spectral data before you decide to use samples in downstream applications. Cuvette compatible models are also available for additional flexibility.

For the first time in NanoDrop history, select NanoDrop Ultra models will include both microvolume absorbance and fluorescence capabilities. Paired with its compact design and large high-resolution 10.1 in. touch screen interface, the NanoDrop Ultra spectrophotometers and fluorometers are a perfect fit for users looking for flexibility and convenience. The optional Acclaro Pro software, compatible with the NanoDrop Ultra instruments, unlocks elevated accuracy for highly concentrated samples with an improved algorithm. This is the next generation NanoDrop single channel instrument with improved hardware and software features over the beloved NanoDrop 2000/2000c and NanoDrop One/One^C Spectrophotometers.

Acclaro Sample Intelligence Technology

Acclaro technology enhances user understanding of sample quality while delivering accurate quantitative measurements. Early identification of contaminants can prevent failure of downstream applications and save days of troubleshooting.

• Contaminant detection and analysis – offers a comprehensive evaluation of sample purity AND corrects sample absorbance, empowering users to confidently identify, quantify, and mitigate contaminants. Plant and bacteria DNA and RNA differentiations are available for researchers, scientists, and professionals in fields such as agriculture, plant biology, microbiology, and genetic engineering.
• Sample integrity insight - provides real-time alerts when bubbles are detected in your sample which could otherwise lead to inaccurate measurements.
• Reliable accuracy – ensures measurement integrity with embedded sensor and digital image analysis.

All-in-one absorbance and fluorescence analysis

Obtain the most complete information about the concentration and quality of your DNA or RNA samples by making absorbance or fluorescence measurements on the same instrument. The NanoDrop Ultra FL and NanoDrop UltraC FL are capable of both micro-volume absorbance and fluorescence measurements, thanks to the inclusion of red and blue solid-state light-emitting diodes (LEDs).

• High sensitivity—more sensitive than absorbance–based quantification
• Sample prep calculator—integrated reagent calculator determines amount of dye and buffer needed.

Tools to aid in 21 CFR Part 11 compliance

Optional Thermo Scientific™ SciVault™ 2 software installs on either the instrument or a companion PC and gives labs the tools they need to comply with US FDA 21 CFR Part 11.

• Compliance made easy – SciVault 2 integrates into the NanoDrop Ultra software user interface and controls user account management, user account access, digital signatures, and audit logs.
• On-board options – software is available to be run directly on the local instrument through on-board user account management or you can connect your instrument to your domain to use your Windows account management.
• Centralized solution - install SciVault 2 software on a central computer to control privileges and view audit logs across multiple NanoDrop Ultra instruments in different labs.

Streamlined workflow

• Fully integrated qPCR recipe calculator - use the built-in library of kits, or add your favorite, to let the software run the math for you. The qPCR recipe calculator suggests how to prepare the reaction based on your sample's concentration.
• Auto-Measure and Auto-Blank functions – multi-sample processing can be streamlined with instant measurements that occur when the pedestal arm is down. These functions can be turned ON or OFF with a single tap on the screen.

Advanced connectivity for data storage, printing and sharing

• Export to the cloud – export data directly to popular cloud storage services like Microsoft OneDrive, Google Drive, and Thermo Fisher Connect.
• Direct LIMS integration – send data directly into your LIMS with the assistance of an integrated RESTful API.
• Easy data-to-printer options – Print your results directly from the NanoDrop Ultra instrument via Wi-Fi, Ethernet or USB printer connection; print exported data from your PC using the Nanodrop Ultra PC Control software.
• Data Your Way – customize and preview the information included in the data file prior to export to ensure it meets any downstream needs.

Accuracy beyond expectations with the Acclaro Pro Software

This optional software package includes new versions of the most popular measurement applications which are unlocked from the factory, providing ±5% Error throughout the absorbance dynamic range.

• Accurate high concentration measurements – absorbance measurements within 5% error up to 550 Abs (10 mm equivalent) – up to 400 mg/mL IgG or 18,000 ng/μL.
• Quick dilution-free process – take triplicate measurements on the pedestal in 2 minutes.
• Enhanced calibration – bundled purchases get an additional calibration from the factory to calibrate the instrument for exceptional accuracy within the Acclaro Pro applications.

For research use only; not for diagnostic purposes.