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Citations & References (25)
Invitrogen™
Oregon Green™ 488 Maleimide
The thiol reactive Oregon Green™ 488 maleimide can be used to can be used to create green fluorescent bioconjugates withRead more
| Catalog Number | Quantity |
|---|---|
| O6034 | 5 mg |
Catalog number O6034
Price (MXN)
-
Quantity:
5 mg
The thiol reactive Oregon Green™ 488 maleimide can be used to can be used to create green fluorescent bioconjugates with excitation/emission maxima ∼496/524 nm.
This fluorinated analog of fluorescein overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ∼ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range.
This fluorinated analog of fluorescein overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ∼ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityThiol
Emission524
Excitation496
Label or DyeOregon Green™ 488
Product TypeMaleimide
Quantity5 mg
Reactive MoietyMaleimide
Shipping ConditionRoom Temperature
Label TypeClassic Dyes
Product LineOregon Green
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.
Citations & References (25)
Citations & References
Abstract
Effect of the substitution of muscle actin-specific subdomain 1 and 2 residues in yeast actin on actin function.
Journal:J Biol Chem
PubMed ID:16882670
'Muscle and yeast actins display distinct behavioral characteristics. To better understand the allosteric interactions that regulate actin function, we created a muscle/yeast hybrid actin containing a muscle-specific outer domain (subdomains 1 and 2) and a yeast inner domain (subdomains 3 and 4). Actin with muscle subdomain 1 and the two
Activation of human acid sphingomyelinase through modification or deletion of C-terminal cysteine.
Journal:J Biol Chem
PubMed ID:12801930
'One form of Niemann-Pick disease is caused by a deficiency in the enzymatic activity of acid sphingomyelinase. During efforts to develop an enzyme replacement therapy based on a recombinant form of human acid sphingomyelinase (rhASM), purified preparations of the recombinant enzyme were found to have substantially increased specific activity if
A pathway of structural changes produced by monastrol binding to Eg5.
Journal:J Biol Chem
PubMed ID:16434397
'Monastrol is a small molecule inhibitor that is specific for Eg5, a member of the kinesin 5 family of mitotic motors. Crystallographic models of Eg5 in the presence and absence of monastrol revealed that drug binding produces a variety of structural changes in the motor, including in loop L5 and
A fluorescent glycolipid-binding peptide probe traces cholesterol dependent microdomain-derived trafficking pathways.
Journal:PLoS ONE
PubMed ID:18716682
'BACKGROUND: The uptake and intracellular trafficking of sphingolipids, which self-associate into plasma membrane microdomains, is associated with many pathological conditions, including viral and toxin infection, lipid storage disease, and neurodegenerative disease. However, the means available to label the trafficking pathways of sphingolipids in live cells are extremely limited. In order
Structure-function relationships in OxlT, the oxalate/formate transporter of Oxalobacter formigenes. Topological features of transmembrane helix 11 as visualized by site-directed fluorescent labeling.
Journal:J Biol Chem
PubMed ID:9651403
'Analysis of hydropathy suggests that in OxlT, the oxalate/formate antiporter of Oxalobacter formigenes, lysine 355 is within transmembrane helix no. 11. To test this idea, we used single-cysteine, histidine-tagged OxlT variants to study the organization of a 30-residue segment (residues 344-373) containing this region. Topology was examined by probing the