Vivid® Regeneration System, 100X

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Description

Vivid® Regeneration System, 100X, is a Vivid® CYP450 Screening Kit component consisting of glucose-6-phosphate and glucose-6-phosphate dehydrogenase, which converts NADP+ into NADPH, which is required to start the CYP450 reaction. Vivid® Regeneration System, 100X, is included in the Vivid® Screening Kits, but may also be purchased separately.

More About Vivid® CYP450 Screening Kits
Vivid® CYP450 Screening Kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and CYP450 inhibition. Vivid® CYP450 Screening Kits include Vivid® Substrate, Vivid® Fluorescent Standard, reaction buffer, Vivid® Regeneration System, NADP+, and CYP450 BACULOSOMES® Plus Reagent. Vivid® Fluorogenic Substrates are blocked dyes that yield minimal fluorescence signal until cleaved or hydroxylated. Oxidation at either of two potential sites releases the highly fluorescent product. CYP450 BACULOSOMES® Plus Reagents are microsomes prepared from insect cells expressing a human CYP450 isozyme and human cytochrome P450 reductase. CYP450 BACULOSOMES® Plus Reagents offer a distinct advantage over human liver microsomes in that only one CYP450 isozyme is expressed, thereby preventing metabolism by other CYP450s.

>> View all Vivid® CYP450 Screening Kits

For Research Use Only. Not for any animal or human therapeutic or diagnostic use.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

For Use With (Equipment): Microplate Reader
Product Line: VIVID®
Product Size: 0.5 mL
Protein Subtype: Coenzymes
Shipping Condition: Dry Ice

Contents & storage

1 tube, Store at -80 °C

Documents

Manuals & protocols

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