BACE1 (β-Secretase) Human Protein

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Description

BACE1 (beta-secretase) is a key enzyme involved in the production of amyloid beta-peptides (Abeta) found in extracellular amyloid plaques of Alzheimer's disease (AD). In some cases early onset familial AD can be attributed to a "Swedish" mutation in the amyloid precursor protein (APP), which dramatically enhances the cleavage of this protein by BACE1. This and other genetic and pathological evidence has led to therapeutic approaches that have focused on the inhibition of BACE1 and other APP-cleaving enzymes, such as gamma-secretase stuff.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Research Category: Neurobiology
Gene ID: 23621
Product Size: 5 units
Protein Subtype: Amyloid-Related Proteins
Shipping Condition: Dry Ice
Species: Human

Contents & storage

Store at -80°C and avoid multiple freeze-thaw cycles.

Documents

Manuals & protocols