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          • Primary Antibodies ›
          • SF3B14 Antibodies

          Invitrogen

          SF3B14 Polyclonal Antibody

          View all (7) SF3B14 antibodies

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          Cite SF3B14 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          SF3B14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          SF3B14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          SF3B14 Antibody (PA5-101771) in IHC (P)

          Immunohistochemistry analysis of SF3B14 in human ovarian cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SF3B14 polyclonal antibody (Product # PA5-101771) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SF3B14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SF3B14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SF3B14 Antibody in Western Blot (WB)
          SF3B14 Polyclonal Antibody

          Product Details

          PA5-101771

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human SF3B6(Accession Q9Y3B4), corresponding to amino acid residues Y92-K125.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2851203

          Product Specific Information

          Antibody detects endogenous levels of total SF3B14.

          Target Information

          SF3B14 encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Pre-mRNA branch site protein p14; SF3B 14 kDa subunit; SF3B14a; spliceosome-associated protein, 14 kDa subunit; Spliceosome-associated protein, 14-kDa; Splicing factor 3B subunit 6; splicing factor 3B, 14 kDa subunit; splicing factor 3B, 14 kDa subunit-like; Splicing factor 3b, subunit 6, 14kDa; unnamed protein product

          View more View less

          Gene Aliases: 0610009D07Rik; 6030419K15Rik; AV001342; CGI-110; HSPC175; HT006; P14; SAP14; SAP14a; SF3B14; SF3B14A; SF3B6

          View more View less

          UniProt ID: (Human) Q9Y3B4, (Mouse) P59708

          View more View less

          Entrez Gene ID: (Human) 51639, (Mouse) 66055, (Rat) 100365504

          View more View less

          Function(s)
          nucleic acid binding RNA binding mRNA binding protein binding nucleotide binding poly(A) RNA binding RNA splicing factor
          Process(es)
          mRNA splicing, via spliceosome blastocyst formation mRNA processing RNA splicing U2-type prespliceosome assembly
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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