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Invitrogen™
Biotin-Ubiquitin
Biotin-labeled ubiquitin for use as a general research tool, or in high throughput assays to monitor protein ubiquitination. Due toMás información
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| Número de catálogo | Cantidad |
|---|---|
| PV4379 | 10 μg |
| PV4380 | 100 μg |
Número de catálogo PV4379
Precio (MXN)
-
Cantidad:
10 μg
Biotin-labeled ubiquitin for use as a general research tool, or in high throughput assays to monitor protein ubiquitination. Due to the method in labeling the ubiquitin protein, all of the lysines with the protein are available for further conjugation to form poly-ubiquitin chains.
For use in combination with other LanthaScreen™ products including LanthaScreen™ Tb-Ubiquitin (Cat. No. PV4375), Fluorescein-Ubiquitin (PV4377), or a LanthaScreen™ antibody such as Tb-anti-biotin (PV4749).
For Research Use Only. Not for use in diagnostic procedures.
Especificaciones
Método de detecciónFluorescence
Excitación/emisión340/490, 520 nm
Para utilizar con (equipo)Microplate Reader
Tipo de etiquetaBiotin & Other Haptens
Etiqueta o tinteBiotin
Cantidad10 μg
Presentación de datosEnd Point
Condiciones de envíoDry Ice
Propiedades de sustratoProtein-Based Substrate
TécnicaTR-FRET
ConjugadoBiotin
FormularioLiquid
Unit SizeEach
Contenido y almacenamiento
Biotin labeled ubiquitin in HEPES buffered saline. Store at -20°C.
Citations & References (1)
Citations & References
Abstract
TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors.
Journal:J Biomol Screen
PubMed ID:22034497
UBC13 is a noncanonical ubiquitin conjugating enzyme (E2) that has been implicated in a variety of cellular signaling processes due to its ability to catalyze formation of lysine 63-linked polyubiquitin chains on various substrates. In particular, UBC13 is required for signaling by a variety of receptors important in immune regulation,