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Thermo Scientific™

JAK2 Recombinant Human Protein, JH1 and JH2 Domains

Catalog number:  PV4393

Related applications:

Protein Assays and Analysis

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Description

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004963
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Target Entry: JAK2 JH1 JH2
Target Gene: Janus kinase 2
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Cytoplasmic, Catalytic
Protein Subtype: Cytoplasmic Tyrosine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 97.8 kDa
Gene Alias: JAK2 JH1 JH2
KinaseFamily: JAK Kinase Family
Protein Length: aa 532-1132
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.