CDK5 plays a critical role in neuron development. The disregulation of the CDK5 and the truncated activator p25 is believed to be involved in neurodegenerative diseases such as Alzheimer's, Parkinson's, and Amyotrophic Lateral Sclerosis. This protein is coexpressed and copurified with p25.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_004926.1 I NP_003876
Molecular Weight
87.7 kDa
Quantity
1 mg
Gene Alias
CDK5/p25, CDK5R
KinaseFamily
CDK and CHK Kinase Family
Recombinant
Yes
Protein Tag
GST Tag, His Tag
Kinase Group
Ser⁄Thr Kinases: CMCG Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Full Length
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development
Contents & Storage
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.