LanthaScreen™ Tb-p4E-BP1 (pThr46) Antibody Kit

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A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 upon stimulation of the pathway.

For use in combination with the GFP-4E-BP1 physiological protein substrate (PV4759) to evaluate inhibitors in medium to high throughput screening applications. An optimized mTor assay buffer (PV4794) is also available.
For Research Use Only. Not for use in diagnostic procedures.


Antibody Molecular Weight: 150000 Da
Excitation⁄Emission (nm): 340⁄490, 520
Format: 384-well plate
Label or Dye: GFP (EmGFP), Tb (Terbium)
Product Line: LanthaScreen®
Product Size: 25 µg
Reactivity: Human
Readout: End Point
Target Enzyme: Serine⁄Threonine Kinases
Technique: TR-FRET
Validated Kinases: FRAP1 (mTOR), FRAP1 (mTOR)
Shipping Condition: Dry Ice

Contents & storage

Terbium-labeled anti-4E-BP1 [pThr46] antibody in HEPES buffered saline. Store at -20°C.


Manuals & protocols