LanthaScreen™ Tb-peIF2a (pSer52) Antibody Kit

Catalog number: PV4810

LanthaScreen™ Tb-peIF2a (pSer52) Antibody Kit

Catalog number: PV4810
Catalog Number
PV4810
Unit Size
25 µg
Price (USD)
3,400.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
19,430.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV481025 µg
3,400.00
Your Price:
***
PV48111 mg
19,430.00
Your Price:
***
Product Overview
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Additional Information
Recommendations
The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.

For use in combination with the GFP-EIF2alpha physiological protein substrate (PV4809) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Antigen
Serine/threonine kinase
Applications
Biochemical Kinase Assays
Conjugate
GFP (EmGFP), Tb (Terbium)
Format
384-well plate
Gene Alias
HPK38, KIAA017
Quantity
25μg
Regulatory Status
RUO
Storage Requirements
–20
Type
Primary
Primary or Secondary
Primary
Gene ID (Entrez)
9833
Packaging
1 Each
Antibody Molecular Weight
150000 Da
Antibody Conjugate
Lanthanide Chelates, Terbium (Tb)
Assay Entry
Biochemical terbium phospho-specific activity
Excitation/Emission
340⁄490, 520
Label or Dye
Tb (Terbium), GFP (EmGFP)
Label Type
Lanthanide Chelates
Reactivity
Human
Shipping Condition
Dry Ice
Readout
End Point
Reactivity abrv
Hu
Target Entry
EIF2AK1, EIF2AK2, EIF2AK3
Target Enzyme
Serine⁄Threonine Kinases
Technique
TR-FRET
Validated Kinases
EIF2AK2, EIF2AK3
Product Line
LanthaScreen™

Contents & Storage

Terbium-labeled anti-eIF2alpha [pSer52] antibody in HEPES buffered saline. Store at -20°C.

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Frequently asked questions (FAQs)

Citations & References