LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit

Catalog number: PV4813

LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit

Catalog number: PV4813
Catalog Number
PV4813
Unit Size
25 µg
Price (USD)
3,215.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
16,630.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV481325 µg
3,215.00
Your Price:
***
PV48141 mg
16,630.00
Your Price:
***
Product Overview
Figures
Videos
Documents
FAQ
Citations & References
Additional Information
Recommendations
A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Applications
Biochemical Kinase Assays
Conjugate
FITC (Fluorescein), Tb (Terbium), lanthanide chelates
Format
384-well plate
Gene Alias
COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, CRAF,NS5,Raf-1,c-Ra, MEKK9,MLK1,PRKE, COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, MEKK7,TAK1,TGF1, MEKK9,MLK1,PRKE, ASK1,MAPKKK5,MEKK, MEKK10,MLK2,MS, MEKK11,MGC17114,MLK-3,MLK3,PTK1,SPR, CRAF,NS5,Raf-1,c-Ra,
Molecular Weight of Antigen
150kDa
Quantity
25μg
Regulatory Status
RUO
Storage Requirements
–20°C
Type
Primary
Primary or Secondary
Primary
Gene ID (Entrez)
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Packaging
1 Kit(s)
Includes
0.02% Sodium azide
Antibody Molecular Weight
150000 Da
Antibody Conjugate
Lanthanide Chelates, Terbium (Tb)
Assay Entry
Biochemical terbium phospho-specific activity
Excitation/Emission
340⁄490, 520
Label or Dye
Tb (Terbium), FITC (Fluorescein)
Label Type
Lanthanide Chelates
Reactivity
Human
Shipping Condition
Dry Ice
Readout
End Point
Reactivity abrv
Hu
Target Entry
MAP3K2, RAF1 (cRAF) Y340D Y341D, MAP3K10, MAP3K9, MAP3K7/MAP3K7IP1, MAP3K5, MAP3K11, BRAF V599E, BRAF, MAP3K8, MAP3K3
Target Enzyme
Serine⁄Threonine Kinases
Technique
TR-FRET
Validated Kinases
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11

Contents & Storage

Terbium-labeled anti-MAP2K1 [pSer217/221] antibody in HEPES buffered saline. Store at -20°C.

Figures

Frequently asked questions (FAQs)

Citations & References