LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit
LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit

LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit

A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a rangeRead more
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Catalog NumberQuantity
PV481325 μg
PV48141 mg
Catalog number PV4813
Price (USD)/ Each
4,615.00
Add to cart
Quantity:
25 μg
Price (USD)/ Each
4,615.00
Add to cart
A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Antibody Molecular Weight150000 Da
Assay EntryBiochemical terbium phospho-specific activity
Excitation/Emission340⁄490, 520
Format384-well Plate
Gene AliasCOT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, CRAF,NS5,Raf-1,c-Ra, MEKK9,MLK1,PRKE, COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, MEKK7,TAK1,TGF1, MEKK9,MLK1,PRKE, ASK1,MAPKKK5,MEKK, MEKK10,MLK2,MS, MEKK11,MGC17114,MLK-3,MLK3,PTK1,SPR, CRAF,NS5,Raf-1,c-Ra,
Gene ID (Entrez)10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Includes0.02% Sodium azide
Molecular Weight of Antigen150kDa
Packaging1 Kit(s)
Primary or SecondaryPrimary
ReactivityHuman
Reactivity abrvHu
ReadoutEnd Point
Research DisciplineTarget and Lead Identification and Validation
Shipping ConditionDry Ice
Target EntryMAP3K2, RAF1 (cRAF) Y340D Y341D, MAP3K10, MAP3K9, MAP3K7/MAP3K7IP1, MAP3K5, MAP3K11, BRAF V599E, BRAF, MAP3K8, MAP3K3
Target EnzymeSerine⁄Threonine Kinases
TechniqueTR-FRET
Validated KinasesBRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
ApplicationsKinase Assay, Enzyme and Protein Activity Assays, Kinase Assay
ConjugateTb (Terbium)/FITC/Lanthanide Chelates
Quantity25 μg
Regulatory StatusRUO, RUO
Unit SizeEach
Contents & Storage
Terbium-labeled anti-MAP2K1 [pSer217/221] antibody in HEPES buffered saline. Store at -20°C.