LanthaScreen™ Tb-pSTAT3 [pTyr705] Antibody Kit

Catalog number:  PV4846

Related applications:

Protein Assays and Analysis

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Description

A part of the JAK/STAT Pathway, STAT3 (Signal Transducer and Activator of Transcription 3) is phosphorylated at Tyr705 by the Janus family of tyrosine kinases.

For use in combination with the GFP-STAT3 physiological protein substrate (PV5212) and the LanthaScreen® STAT3 GripTite™ cell line (K1488) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Antibody Conjugate: Lanthanide Chelates, Terbium (Tb)
Antibody Molecular Weight: 150000 Da
Antigen: Tyrosine kinases
Assay Entry: Cell-based terbium phospho-specific activity (stable)
Excitation/Emission: 340⁄490, 520
Label Type: Lanthanide Chelates
Label or Dye: Tb (Terbium), GFP (EmGFP)
Reactivity: Human
Reactivity abrv: Hu
Readout: End Point
Shipping Condition: Dry Ice
Target Entry: STAT3
Target Enzyme: Tyrosine Kinases
Technique: TR-FRET
Validated Kinases: JAK1, JAK2, JAK3, TYK2
Applications: Biochemical Kinase Assays
Concentration: 0.48mg/mL
Conjugate: GFP (EmGFP), Tb (Terbium), lanthanide chelates
Format: 384-well plate
Molecular Weight of Antigen: 150kDa
Quantity: 25μg
Regulatory Status: RUO
Storage Requirements: –20°C
Type: Primary
Primary or Secondary: Primary
Packaging: 1 Kit(s)

Contents & storage

Terbium-labeled anti-STAT3 [pTyr705] antibody in HEPES buffered saline. Store at -20°C.