LanthaScreen™ Tb-pERM (pLRRKtide) Antibody Kit

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A phospho specific antibody directed to the ezrin/radixin/moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease.

For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.


Antibody Molecular Weight: 150000 Da
Excitation⁄Emission (nm): 340⁄490, 520
Format: 384-well plate
Gene ID: 120892
Label or Dye: FITC (Fluorescein), Tb (Terbium)
Product Line: LanthaScreen®
Product Size: 25 µg
Reactivity: Human
Readout: End Point
Target Enzyme: Serine⁄Threonine Kinases
Technique: TR-FRET
Validated Kinases: LRRK2
Shipping Condition: Dry Ice

Contents & storage

Terbium-labeled anti-ERM [pLRRKtide] antibody in HEPES buffered saline. Store at -20°C.


Manuals & protocols