Fluorescein-ERM (LRRKtide)

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Description

A fluorescein-labeled peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants.

For use in combination with the LanthaScreen® Tb-anti-ERM (pLRRKtide) Antibody (PV4899) to evalute inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Amino Acid Sequence: Fluorescein-GAGRLGRDKYKTLRQIRQ
Detection Method: Fluorescent
Gene ID: 120892
Label or Dye: FITC (Fluorescein)
Molecular Weight: 2475.8 Da
Product Size: 1 mg
Substrate: ERM (LRRKtide)
Substrate Properties: Peptide-Based Substrate
Substrate Type: Kinase Substrate
Target Enzyme: Serine⁄Threonine Kinases
Validated Kinases: LRRK2
Shipping Condition: Dry Ice

Contents & storage

Fluorescein-ERM (LRRKtide) peptide substrate in water. Store at -20°C.

Documents

Manuals & protocols