A peptide substrate based upon the C-terminal tail of RNA Polymerase II that is a reported substrate for Cyclin Dependent Kinases (CDK7, CDK8 and CDK9). For use with the Adapta™ Universal Kinase Assay (PV5099).
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Amino Acid Sequence
YSPTSPSYSPTSPSYSPTSPSKKKK
Assay Entry
Biochemical ADP accumulation
Detection Method
Fluorescent
Quantity
1 mL
Substrate
peptide based upon the C-terminal tail of RNA Polymerase II
Substrate Properties
Peptide-Based Substrate
Substrate Type
Kinase Substrate
Target Enzyme
Serine/Threonine Kinases
Gene ID (Entrez)
1022, 3376
Molecular Weight (g/mol)
2689.9 Da
Shipping Condition
Dry Ice
Target Entry
CDK9/Cyclin T1, CDK7
Validated Kinases
CDK7, CDK9
Contents & Storage
2 mM CDK7/9tide peptide substrate in 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2 and 1 mM EGTA. Store at -20°C.