A part of the PI3K/AKT Pathway, PDCD4 (programmed cell death protein 4) is phosphorylated at Ser457 indirectly via mTORC1 (through the ribosomal protein p70 S6 kinase).
For use in combination with the LanthaScreen™ PDCD4 HEK293E cell line (K1593) to evaluate inhibitors in medium to high throughput screening applications..
For Research Use Only. Not for use in diagnostic procedures.