LanthaScreen™ Tb-anti-phospho-p53 [pSer15] Antibody Kit

Catalog number:  PV5130

Related applications:

Pharma & Biopharma

| Oncology & Genetic Disease Research

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Description

The p53 tumor suppressor protein is an essential component of many different signaling pathways. The LanthaScreen® antibody detects the phosphorylation of p53 at Ser15 by a range of kinases including DNA-PK, ATM, and ATR.

For use in combination with the Fluorescein-p53 (Ser15) peptide substrate (PV5132) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Antibody Conjugate: Lanthanide Chelates, Terbium (Tb)
Antibody Molecular Weight: 150000 Da
Antigen: Serine/threonine kinase
Assay Entry: Biochemical terbium phospho-specific activity
Excitation/Emission: 340⁄490, 520
Label Type: Lanthanide Chelates
Label or Dye: Tb (Terbium), FITC (Fluorescein)
Product Line: LanthaScreen®
Reactivity: Human
Reactivity abrv: Hu
Readout: End Point
Shipping Condition: Dry Ice
Target Entry: DNAPK
Target Enzyme: Serine⁄Threonine Kinases
Technique: TR-FRET
Applications: Biochemical Kinase Assays
Concentration: 0.53mg/mL
Conjugate: FITC (Fluorescein), Tb (Terbium), lanthanide chelates
Format: 384-well plate
Molecular Weight of Antigen: 150kDa
Quantity: 25μg
Regulatory Status: RUO
Storage Requirements: –20°C
Type: Primary
Primary or Secondary: Primary
Packaging: 1 Kit(s)

Contents & storage

Terbium-labeled anti-phospho-p53 [pSer15] antibody in HEPES buffered saline. Store at -20°C.