A fluorescein-labeled peptide substrate based upon p53 containing Ser15. p53 is phosphorylated at Ser15 by a wide range of kinases including PI3K/AKT pathway kinases such DNA-PK, ATM, and ATR.
For use in combination with the LanthaScreen™ Tb-anti-phospho-p53 [pSer15] antibody (PV5130) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Amino Acid Sequence
Fluorescein-EPPLSQEAFADLWKK
Assay Entry
Biochemical terbium phospho-specific activity
Detection Method
Fluorescent
Product Line
LanthaScreen™
Quantity
1 mL
Substrate
Fluorescein-Tb
Substrate Properties
Peptide-Based Substrate
Substrate Type
Kinase Substrate
Target Enzyme
Serine/Threonine Kinases
Label or Dye
FITC (Fluorescein)
Molecular Weight (g/mol)
2118.3 Da
Shipping Condition
Dry Ice
Target Entry
DNAPK
Contents & Storage
1 mg/mL Fluorescein-p53 (Ser15) peptide substrates in DMSO. Store at -20° C and protect from light.